The drugs we are currently trying to use are based on the inhibition of enoyl reductase. There is a brief explanation in Find-A-Drug, where we got our list of molecules to make.

Describe in terms that even non-scientists can understand what that means and the related facts. For example,

  1. Are there any approved drugs using the inhibition of enoyl reductase?
  2. How are new anti-malarial drugs tested?
  3. What are problems with the existing drugs to treat malaria?
  4. How do chemists decide which molecules to make to make a new drug against malaria?
  5. Besides enoyl reductase, what are the other enzymes targeted to fight malaria?
  6. Are there political barriers to treating malaria?
  7. Are there religious barriers to treating malaria?
  8. Which is more important - treating malaria with drugs or killing mosquitoes? Do compounds like DDT do more harm than good?